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NSUOCO Residency Program Advanced Search Exercises 2017

Clinical Question (PICO):

In patients with primary open angle glaucoma, do topical medications to reduce intraocular pressure versus no treatment delay visual field defect progression?


1. Clinical Key. Search all content types for background information and images on “primary open angle glaucoma”.

From the Optometry page, click on Clinical Key under Research & Clinical Databases.

Register, Login, and enter one or two words of your main search concept.

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The results screen is divided into 3 sections.

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You will find background information from a variety of resources, such as, a Disease Overview from the 2017 Conn’s Current Therapy (right sidebar). The main results section in the center of the page displays an evidence summary in First Consult, full text book chapters, and journal articles.

Move your cursor over the titles of citations in the main results section to display the icons to save, email, or print.

Under FIRST CONSULT, click on “Primary open-angle glaucoma” to open the Evidence Summary.

Scroll through the sections of the Evidence Summary from the left sidebar. Under “Treatment”, click on “Medications”.

Comments and summaries on medications will be followed by an “Evidence” section where RCTs and Systematic Reviews will be summarized and “graded” with an evidence level, e.g., 1 or 2.

Links are provided to the list of references with complete citations to the articles and systematic reviews.

Scroll to the top of the page, and click on “Back to Results”.

From the Filters on the left sidebar, scroll down under “Source Type” and select “Images”.

Click on an image you want to use for a presentation.

Click on the “add to presentation” icon.

Select or create a new presentation and save the image to it.

Pull down the menu under your login name and click on “presentations”.

Click on the saved image and click on “Export”.

The image will be saved to PowerPoint along with the copyright information. You are required by the publisher to include this information on your slide presentation, regardless of setting.

Watch the Clinical Key video on the Optometry A-Z page to review the above steps anytime.

Close the PowerPoint presentation. Click the search icon to return to your search results.

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2. Clinical Key. Locate randomized control trials and systematic reviews on treatment of “primary open angle glaucoma”.

In the Clinical Key search box, add “eye drops” to the original search for “primary open angle glaucoma” and press the search icon.

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Under Source Type, click the box next to “Journal Articles” and the button beside “Full text and MEDLINE”.

Check the box beside “Randomized Control Trials”. Your search results are now limited to articles that report original research data.

Scroll the citations and click on the download PDF icon to display full text that is available in Clinical Key.

Check the boxes beside interesting citations that are NOT available in full text in Clinical Key, e.g., articles from Experimental Eye Research and Journal of Glaucoma. Scroll to the top of the main results section. The number of citations you have checked appears beside the icons to save, email, or print. Click the icon to print citations you have marked:

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Save the printout and use it to locate full text in other resources (See examples in NSUOCO Residency Program Basic Exercises for this course).

Under Source Type, uncheck “Randomized Control Trials”.

Check the box beside “Systematic Reviews”.

{Reminder: A systematic review is a critical assessment of existing evidence that addresses a focused clinical question, includes a comprehensive literature search, appraises the quality of studies, and reports results in a systematic manner. If the studies report comparable quantitative data and have a low degree of variation in their findings, a meta-analysis can be performed to derive a summary estimate of effect.}

Scan the list of systematic reviews. Click on the download PDF icon to display full text of systematic reviews published in journals, e.g., Survey of Ophthalmology.

Save and print the citation to a systematic review published in the Cochrane Library of Systematic Reviews, “Neuroprotection for treatment of glaucoma in adults” published in 2017. You can locate the full text of it in other resources (see exercise No. 3 below).

Logout of Clinical Key and return to the Optometry web page.

3. Cochrane Systematic Reviews. Locate the full text of the systematic review from your Clinical Key search on “primary open angle glaucoma”.

From the Optometry web page, click on Cochrane Systematic Reviews under Research & Clinical Databases.

Click on “EBM Reviews – Cochrane Database of Systematic Reviews”.

Select “title” and enter “neuroprotection for treatment of glaucoma in adults” and press Search.

Click on “EBM Full Text” and click on “Article as PDF”.

Scan the objectives, search methods, selection criteria, main results, and authors’ conclusions from the abstract. Note that all studies included in the review as well as all studies that were excluded from the review are listed.

At the top of the page, return to Ovid search results.

At the top of the main page, from the blue bar, click on “Cochrane”.

A list displays of all of the Cochrane research groups. Scroll down to “Eyes and Vision Group” and click on “table of contents”. There are currently 237 Cochrane reviews published by this group.

Logoff Ovid and return to the Optometry web page.


4. UpToDate. Search for an evidence based summary on treatment of “primary open angle glaucoma”.

From the Optometry Web Page, click on “UpToDate” under Research & Clinical Databases.

Enter “primary open angle glaucoma”. From the list of summaries, select “Open-angle glaucoma: Treatment”.

At the top of the summary, note the dates of the latest literature review and topic update.

Scan the summary and read the section on “Pharmacologic Therapy”.

In paragraph one, click on the link to “table 1”.

In the upper right hand corner of the page, click on “Export to PowerPoint”.

Open the PowerPoint file and note the copyright information has been automatically included with the figure. You are required by the publisher to include this information on your slide presentations, regardless of setting.

Click the back arrow to return to the evidence summary.

From the left sidebar, click on “Target Intraocular Pressure”.

Scroll through the section and note references to data from the EMGT and CIGTS studies.

From the left sidebar, click on “Summary and Recommendations”.

Does this section provide answers to the clinical question?

How is “Grade1B” defined? --- Watch the UpToDate video for an overview of "Graded Recommendations"

Watch the UpToDate video for an overview of "Graded Recommendations"

Are complete references provided to studies cited in the literature review that enable you to consult the original data?

Approximately how many minutes did it take for you to find an answer to the clinical question?

Return to the Optometry web page.

5. Ovid MEDLINE. Search for “case reports” on the use of “optical coherence tomography to detect and manage diabetic retinopathy”.

From the Optometry web page, click on the link to MEDLINE under Research & Clinical Databases.

Click on Ovid MEDLINE ® Epub Ahead of Print, In-Process & Other Non-Indexed Citations, Ovid MEDLINE ® Daily and Ovid MEDLINE ® 1946-present.

From the search box, enter “optical coherence tomography” and press Search.

Note the subject heading is “tomography, optical coherence”.

Click the box next to the subject heading and click the box under “explode”.

Click the box next to the keyword “optical coherence tomography” and press Continue. From the search box, enter “diabetic retinopathy” and press Search.

Note the subject heading is “diabetic retinopathy”.

Click the box next to the subject heading and click the box under “explode”.

Click the box next to the keyword “diabetic retinopathy” and press Search.

In the search box, enter “1 and 2” to locate articles that discuss both concepts.

There are over 2,000 articles on your topic.

Scroll down the page, and click on “Additional Limits” in the blue box.

On the right hand side of the limits page, find the section on “Publication types” and select “case reports”.

Click on “Limit a Search”.

There are 165 case reports on your topic.

Display the results. Scroll through the citations and click on “Article as PDF” or “Full Text” links.

Click the boxes beside citations that do not include a “PDF” or “full text” icon. At the top of the search results page, select “Print” or “Email”.

Save the printout and use it to locate full text in other resources (See examples in NSUOCO Residency Program Basic Exercises for this course).

How would you obtain full text of this article?

Multifocal electroretinography changes in the macula at high altitude: a report of three cases.
Pavlidis M; Stupp T; Georgalas I; Georgiadou E; Moschos M; Thanos S.
Ophthalmologica. 219(6):404-12, 2005 Nov-Dec.
[Case Reports. Journal Article]
UI: 16286804
Authors Full Name
Pavlidis, Mitrofanis; Stupp, Tobias; Georgalas, Ilias; Georgiadou, Evi; Moschos, Michail; Thanos, Solon.


Return to the Ovid Search Form

Leave the citations checked that you printed or emailed

At the top of the search results page, select “export”

Complete the Export Citation List Menu as shown below

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NOTE: Exporting and working with citations in RefWorks requires registration.

1. See Page 3 of the NSUOCO User Guide for registration and access instructions

2. See Pages 17-21 of the NSUOCO User Guide for help with writing your paper and creating a bibliography

3. Click here to see how to quickly create a short reference list to use in slides and presentations

Logoff Ovid and return to the Optometry web page






Page maintained by: Sandra Martin marti004@nsuok.edu
Last update: September 20, 2017